Dr O'Brien qualified from Guys and St Thomas' Medical School in 1994. He completed gastroenterology and general medicine training on the South Thames rotation and his hepatology training at King's College, The Royal London and University College London Hospitals (UCLH). Alastair undertook a PhD at University College London as a Medical Research Training Fellow.
Dr O'Brien was appointed as Consultant and Clinical Senior Lecturer in Hepatology at UCLH and The Royal Free Hospitals in 2007. He is responsible for the inpatient management of all causes of acute and chronic liver disease at UCLH. He sees outpatients at the Royal Free Hospital and his practise includes non-alcoholic fatty liver disease, autoimmune hepatitis, primary biliary cirrhosis , viral hepatitis (B & C), metabolic and alcohol related liver disease. Alastair is skilled in upper GI endoscopy especially management of variceal bleeding. He aims to put his patients at ease and attend to their problems in a relaxed and thorough manner.
Dr O'Brien has recently been awarded 1.6 million pounds from the Wellcome Trust and Department of Health to fund a multi-centre clinical trial to prevent infection in cirrhosis patients. He also has funding from the Medical Research Council, The UCLH Biomedical Research Centre, and Industry (Pfizer). Dr O'Brien has published papers in many leading journals including Nature Medicine,The Lancet, Gastroenterology, Hepatology and Proceedings of The National Academy of Science.
Alastair sees patients for clinic appointments on a Monday and Wednesday between 5 and 8pm at 47 Nottingham Place and endoscopy on Wednesday 2-6pm or Friday 3-5pm.